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・ Gonadarche
・ Gonadish
・ Gonadoblastoma
・ Gonadosomatic Index
・ Gonadotropic cell
・ Gonadotropin
・ Gonadotropin preparations
・ Gonadotropin receptor
・ Gonadotropin release inhibitor
・ Gonadotropin-releasing hormone
・ Gonadotropin-releasing hormone agonist
・ Gonadotropin-releasing hormone analogue
・ Gonadotropin-releasing hormone antagonist
・ Gonadotropin-releasing hormone family
・ Gonadotropin-releasing hormone insensitivity
Gonadotropin-releasing hormone receptor
・ Gonadotropin-resistant ovary syndrome
・ Gonaepa
・ Gonaepa actinis
・ Gonaepa dysthyma
・ Gonaepa heliarcha
・ Gonaepa josianella
・ Gonag
・ Gonagala massacre
・ Gonaganur
・ Gonagas
・ Gonagyra
・ Gonaha
・ Gonahran
・ Gonakudzingwa Restriction Camp


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Gonadotropin-releasing hormone receptor : ウィキペディア英語版
Gonadotropin-releasing hormone receptor

The gonadotropin-releasing hormone receptor (GNRHR), also known as the luteinizing hormone releasing hormone receptor (LHRHR), is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate.
This receptor is a 60 kDa G protein-coupled receptor and resides primarily in the pituitary and is responsible for eliciting the actions of LHRH after its release from the hypothalamus. Upon activation, the LHRHr stimulates tyrosine phosphatase and elicits the release of LH from the pituitary.
Evidence exists showing the presence of LHRH and its receptor in extrapituitary tissues as well as a role in progression of some cancers.
== Function ==
Following binding of Gonadotropin releasing hormone (GNRH), GNRHR associates with G-proteins that activate a phosphatidylinositol (PtdIns)-calcium second messenger system. Activation of GNRHR ultimately causes the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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